Blar i forfatter "Nossent, Johannes C"
-
Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis
Becker-Merok, Andrea; Kalaaji, Manar; Haugbro, Kaia; Nikolaisen, Cathrin; Nilsen, Kirsten; Rekvig, Ole Petter; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-10-24)This study investigated the overall clinical impact of anti-α- actinin antibodies in patients with pre-selected autoimmune diseases and in a random group of anti-nuclear antibody (ANA)- positive individuals. The relation of anti-α-actinin antibodies with lupus nephritis and anti-double-stranded DNA (anti-dsDNA) antibodies represented a particular focus for the study. Using a cross-sectional ... -
BAFF expression is increased in Lupus Nephritis and associated with activation of C1 inhibitor, α-1-acid-glycoprotein and endothelial markers.
Eilertsen, Gro Østli; Ghelue, Marijke van; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)B cell activating factor (BAFF) inhibitor therapy has recently been approved for non-renal Systemic Lupus Erythematosus (SLE). While BAFF plays a role in experimental lupus nephritis (LN), its role human LN is not well studied. Case control study in 102 SLE patients, 30 with LN (+LN) and 72 without LN (-LN) and 31 healthy controls. We analysed BAFF mRNA expression in PBMCs (BAFF-RQ) and serum BAFF ... -
CHRONIC NASAL CARRIAGE OF STAPHYLOCOCCUS AUREUS DOES NOT INCREASE THE RISK OF RELAPSE AND SEVERE INFECTIONS IN GRANULOMATOSIS WITH POLYANGIITIS PATIENTS WHEN RECEIVING RITUXIMAB MAINTENANCE TREATMENT
Besada, Emilio; Koldingsnes, Wenche; Nossent, Johannes C (Conference object; Konferansebidrag, 2014-06-10) -
Chronic nasal carriage of Staphylococcus aureus in granulomatosis with polyangiitis patients receiving rituximab maintenance: friend or foe?
Besada, Emilio; Koldingsnes, Wenche; Nossent, Johannes C (Journal article; Tidsskriftartikkel, 2014) -
Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational study
Compagno, Michele; Rekvig, Ole Petter; Bengtsson, Anders; Sturfeld, Gunnar; Heegaard, Niels H. H.; Jönsen, Andreas; Jacobsen, Rasmus S.; Eilertsen, Gro Østli; Fenton, Christopher Graham; Truedsson, Lennart; Nossent, Johannes C; Jacobsen, Søren (Journal article; Tidsskriftartikkel, 2014) -
CRP as a marker for myocardial infarction and for damage accrual in systemic lupus erythematosus patients: results from a single-centre longitudinal study
Besada, Emilio; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)CRP is a marker of inflammation and is also a known cardiovascular risk factor. Patients with systemic lupus erythematosus (SLE) have moderately elevated CRP levels and develop organ damage , that includes an increased rate of cardiovascular events. -
CRP as a marker for myocardial infarction and for damage accrual in systemic lupus erythematosus: results from a single-center longitudinal study.
Besada, Emilio; Nossent, Johannes C (Conference object; Konferansebidrag, 2012) -
Cyclophosphamide effect on immunoglobulins levels in AAV patients treated with long-term pre-emptive rituximab maintenance.
Besada, Emilio; Koldingsnes, Wenche; Nossent, Johannes C (Conference object; Konferansebidrag, 2013) -
Diagnostic value of antibodies against mutated citrullinated vimentin for rheumatoid arthritis
Besada, Emilio; Nikolaisen, Cathrin; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)OBJECTIVES: To compare the diagnostic efficiency of anti-MCV, anti-CCP2 and RF detection for patients with RA. METHODS: Cross-sectional study of patients with established rheumatic disease: rheumatoid arthritis (RA; n=75), psoriatic arthritis (PsA; n=25), 27 patients with ankylosing spondylitis (AS; n=27) and connective tissue disease (CTD; n=17). Anti-CCP2, anti-MCV and RF were detected by ... -
Efficacy of chronic pre-emptive rituximab treatment in ANCA-associated vasculitis
Besada, Emilio; Nossent, Johannes C (Conference object; Konferansebidrag, 2012) -
Efficacy of chronic pre-emptive rituximab treatment in ANCA-associated vasculitis
Besada, Emilio; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2012) -
Epidemiology of ANCA associated vasculitis
Nossent, Johannes C; Koldingsnes, Wenche (Journal article; Tidsskriftartikkel; Peer reviewed, 2008) -
Increased levels of BAFF in patients with Systemic Lupus Erythematosus are associated with acute phase reactants, independent of BAFF genetics: a case control study
Eilertsen, Gro Østli; Van Ghelue, Marijke; Nossent, Johannes C (Journal article; Tidsskriftartikkel, 2011)Objectives. To determine whether increased levels of B-cell activating factor (BAFF) in patients with SLE are due to disease activity or genetic variations in the promoter region of the BAFF gene and BAFF gene expression. Methods. The case-control study included 101 SLE patients and 111 healthy controls. Five single nucleotide polymorphisms (SNPs) in the BAFF promoter region were investigated by ... -
The Influence of the 1997 Updated Classification Criteria for Systemic Lupus Erythematosus : Epidemiology, Disease Presentation, and Patient Management
Eilertsen, Gro Østli; Becker-Merok, Andrea; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2009)The influence of the 1997 updated classification criteria for systemic lupus erythematosus: epidemiology, disease presentation, and patient management. Eilertsen GØ, Becker-Merok A, Nossent JC. Department of Rheumatology, Medical School, University of Tromsø, 9037 Tromsø, Norway. gro.ostli.eilertsen@unn.no OBJECTIVE: The 1997 update of the American College of Rheumatology classification ... -
Long-term efficacy and safety of pre-emptive maintenance therapy with rituximab in Granulomatosis with Polyangiitis: results from a single centre.
Besada, Emilio; Koldingsnes, Wenche; Nossent, Johannes C (Conference object; Konferansebidrag, 2013)Objective: Rituximab (RTX) is an anti-CD20 antibody used successfully in Granulomatosis with Polyangiitis (GPA) for induction and maintenance of remission. Our study aims to evaluate the long term efficacy and safety of chronic pre-emptive RTX therapy in GPA. -
Long-term efficacy and safety of pre-emptive maintenance therapy with rituximab in Granulomatosis with Polyangiitis: results from a single centre.
Besada, Emilio; Koldingsnes, Wenche; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Rituximab (RTX) is an anti-CD20 antibody used successfully in granulomatosis with polyangiitis (GPA) for induction and maintenance of remission. Our study aims to evaluate the long-term efficacy and safety of chronic pre-emptive RTX therapy in GPA. Retrospective study of 35 GPA patients treated with RTX between April 2004 and September 2011 for active disease and maintenance. RTX was initiated as ... -
Low CD4/CD8 ratio is associated with lower immunoglobulin levels in granulomatosis with polyangiitis patients receiving rituximab
Besada, Emilio; Nossent, Johannes C (Journal article; Tidsskriftartikkel, 2014-09-03) -
Low CD4/CD8 ratio is associated with lower immunoglobulin levels in granulomatosis with polyangiitis patients receiving Rituximab
Besada, Emilio; Nossent, Johannes C (Journal article; Tidsskriftartikkel, 2014) -
Low copy number of the FCGR3B gene and rheumatoid arthritis: a case-control study and meta-analysis
Graf, S; Lester, Susan; Nossent, Johannes C; Hill, C; Proudman, S. M; Lee, A; Rischmueller, Maureen (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-02-07)Introduction: Low copy number (CN) of the Fc gamma receptor 3B (FCGR3B) gene has been associated with systemic autoimmune disease. This receptor for IgG is present almost exclusively on neutrophils and plays a role in their interaction with immune complexes. At present the relationship between FCGR3B and rheumatoid arthritis (RA) is unclear. The aim of the present study was to investigate whether ... -
Serum immunoglobulin levels and risk factors for hypogammaglobulinaemia during long-term maintenance therapy with rituximab in patients with granulomatosis with polyangiitis
Besada, Emilio; Koldingsnes, Wenche; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-05-15)